Research Peptide Vials
KPV
KPV is a C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone (α-MSH). Research has examined its potent anti-inflammatory activity, primarily via inhibition of NF-κB and modulation of pro-inflammatory cytokines in intestinal and skin tissue models.
Product Name: | α-MSH (11-13) (free acid) |
Synonyms: | α-Melanotropin(11-13);α-Melanotropin(11-13)[human];α-Melanotropin(11-13)[pig];α-MSH(11-13)[human];α-MSH(11-13)[pig];a-MSH (11-13) (free acid);H-LYS-PRO-VAL-OH ACETATE SALT;H-LYS-PRO-VAL-OH ACOH |
CAS: | 67727-97-3 |
MF: | C16H30N4O4 |
MW: | 342.43 |
EINECS: | 208-856-8 |
Product Categories: | Research Peptide |
α-MSH (11-13) (free acid) is also known as KPV (L-Lys-L-Pro-L-Val), exhibited anti-inflammation without induction of cutaneous pigmentation in a frog skin bioassay.It has been used as an antiinflammatory agent in the treatment of inflammatory bowel disease and bowel disease. It is also being studied as a contraceptive and an elastase inhibitor. This drug has shown some promise in the treatment of autoimmune diseases, such as rheumatoid arthritis, Crohn's disease, ulcerative colitis, multiple sclerosis, and type 1 diabetes mellitus. It is thought that α-MSH (11-13) (free acid) acetate salt may inhibit the production of inflammatory cells by inhibiting leukocyte elastase activity.